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AI-native healthcare interoperability

Translate any healthcare format to any other — in days

Health1st is the universal translator for healthcare data. One AI-native engine converts bidirectionally across HL7 v2, FHIR, C-CDA, X12, NCPDP and DICOM, so you clear interface backlogs, meet CMS-0057-F, and modernize without rip-and-replace.

  • Any format to any format, bidirectional by design
  • AI maps it; your team approves it, with a full audit trail
  • Runs in your environment, so you keep control of PHI
Explore the platform

Built for HIPAA, HITECH & SOC 2

HIPAAHITECHSOC 2
HL7 v2.x
ADT · ORU · ORM
FHIR R4/R5
US Core · IPS
C-CDA / CDA
CCD · documents
X12 EDI
270/271 · 278 · 837
AI Transformation Engine
any format ↔ any format · bidirectional · validated
NCPDP
SCRIPT · RTPB
DICOM
imaging metadata
Direct
secure messaging
Flat files
CSV · JSON · XML
Diagram: eight healthcare data formats — HL7 v2.x, FHIR R4/R5, C-CDA, X12 EDI, NCPDP, DICOM, Direct, and flat files (CSV/JSON/XML) — all connect bidirectionally through a single AI transformation engine that maps, validates, and converts any format to any other.
Any↔Any
formats & standards
HL7 · FHIR · X12 · NCPDP · more
12
AI interoperability agents
mapping to pharmacy
Days
to first interface
not weeks or months
US Core
conformance built in
R4.0.1 validated
One engine, every standard

One engine for every healthcare format

A single hospital runs HL7 v2 for admissions, FHIR for apps, X12 for claims, NCPDP for prescriptions, and DICOM for imaging — all at once. Health1st speaks them all, in both directions.

HL7 v2.x ⇄ FHIR

ADT, ORU, ORM, SIU, MDM and more ↔ US Core FHIR resources — both directions.

C-CDA / CDA

Parse and generate CCD and clinical documents ↔ FHIR Composition & DocumentReference.

X12 EDI

270/271 eligibility, 278 prior auth, 837/835 claims ↔ FHIR & Da Vinci.

NCPDP

SCRIPT e-prescribing and Real-Time Prescription Benefit ↔ FHIR MedicationRequest.

DICOM

Imaging metadata and structured reports ↔ FHIR ImagingStudy.

Direct & IHE

Secure Direct messaging and XDS/MHD cross-community document exchange.

Flat & custom

CSV, JSON, XML, fixed-width, Z-segments and proprietary formats.

Terminology

ICD-10, SNOMED CT, LOINC, CPT, RxNorm and NDC crosswalks.

See the actual transformation — pick a format

HL7 v2.5.1 · ADT^A01inbound
MSH|^~\&|EPIC|HOSP|H1ST|DST|202601..||ADT^A01|
PID|1||MRN12345^^^HOSP^MR||DOE^JOHN^A||
    19701225|M|||123 MAIN ST^^AUSTIN^TX
PV1|1|I|ICU^101^A|||...admit...
DG1|1|I10|E11.9^Type 2 diabetes mellitus
PIDPatient
PV1Encounter
DG1Condition
AIMapping
Agent
validate · normalize · map
FHIR R4 · Bundleoutbound
{ "resourceType": "Patient",
  "identifier": [{ "value": "MRN12345" }],
  "name": [{ "family": "Doe",
             "given": ["John","A"] }],
  "gender": "male",
  "birthDate": "1970-12-25" }

{ "resourceType": "Condition",
  "code": { "coding": [{
    "system": "…/icd-10-cm",
    "code": "E11.9" }] } }
US CoreR4.0.1validated
An inbound HL7 v2.5.1 ADT^A01 admission message is parsed segment by segment — PID maps to a FHIR Patient, PV1 to an Encounter, and the DG1 diagnosis segment (ICD-10 E11.9, Type 2 diabetes) to a FHIR Condition — by the AI Mapping Agent, validated against US Core and FHIR R4.0.1. The reverse direction (FHIR back to HL7 v2) is also supported.

See the full protocol matrix on the platform page →

The problem

Interoperability is stuck between a deadline and a backlog

Healthcare data still speaks HL7 v2, while regulators and partners demand FHIR. Bridging the two by hand is slow and expensive.

Interface backlogs measured in months

Every new HL7 v2 interface is hand-built and hand-tested by scarce, expensive integration analysts. Projects slip; roadmaps stall.

A 2027 deadline that won't move

CMS-0057-F requires four FHIR APIs by January 1, 2027. As of late 2025, roughly 43% of payers hadn't started. The clock is the project.

Must expose FHIR, still run HL7 v2

The Cures Act mandates a FHIR API in every certified EHR, but the operational reality is still v2. That gap is exactly what we close.

How it works

An AI-native pipeline, with humans in the loop

Every message flows through the same four stages. AI does the heavy lifting; your analysts review and approve before anything ships.

  1. 1

    Ingest

    Connect any source (EHR, lab, pharmacy, payer) over HL7 v2, FHIR, X12, NCPDP or flat files.

  2. 2

    AI map

    The Mapping & Terminology agents draft field and code mappings and explain every decision.

  3. 3

    Validate

    The Validation agent checks output against US Core, Da Vinci and IPS profiles before release.

  4. 4

    Deliver

    The Orchestration agent routes, retries and guarantees delivery — real-time, batch or streaming.

A real translation: HL7 v2 → FHIR

HL7 v2.5.1 · ADT^A01inbound
MSH|^~\&|EPIC|HOSP|H1ST|DST|202601..||ADT^A01|
PID|1||MRN12345^^^HOSP^MR||DOE^JOHN^A||
    19701225|M|||123 MAIN ST^^AUSTIN^TX
PV1|1|I|ICU^101^A|||...admit...
DG1|1|I10|E11.9^Type 2 diabetes mellitus
PIDPatient
PV1Encounter
DG1Condition
AIMapping
Agent
validate · normalize · map
FHIR R4 · Bundleoutbound
{ "resourceType": "Patient",
  "identifier": [{ "value": "MRN12345" }],
  "name": [{ "family": "Doe",
             "given": ["John","A"] }],
  "gender": "male",
  "birthDate": "1970-12-25" }

{ "resourceType": "Condition",
  "code": { "coding": [{
    "system": "…/icd-10-cm",
    "code": "E11.9" }] } }
US CoreR4.0.1validated
An inbound HL7 v2.5.1 ADT^A01 admission message is parsed segment by segment — PID maps to a FHIR Patient, PV1 to an Encounter, and the DG1 diagnosis segment (ICD-10 E11.9, Type 2 diabetes) to a FHIR Condition — by the AI Mapping Agent, validated against US Core and FHIR R4.0.1. The reverse direction (FHIR back to HL7 v2) is also supported.

CMS-0057-F is a deadline, not a project

Impacted payers must run four FHIR APIs by January 1, 2027, with operational provisions starting in 2026. Health1st gets you there — mapping, PARDD prior auth, and conformance included.

See the 2027 readiness path
How we compare

AI-native, built for speed

Legacy engines can take 6–12 weeks and $10K–$30K+ to stand up a single interface; managed API networks lock you into their cloud and per-transaction fees. Health1st is built for speed, on-prem/VPC control, and transparent pricing.

CapabilityHealth1stRedoxRhapsodyMirth (OSS)
Bidirectional HL7 v2 ↔ FHIR
AI-native mapping (drafts + validates)
No-code mapping studio
Deploy on-prem / in your VPC
Transparent, usage-based pricing
Days to first interface

Comparison reflects public positioning; capabilities and pricing vary by deployment. See detailed comparisons.

Security & Compliance

Where our compliance actually stands

Protecting PHI is non-negotiable. Here's exactly where our certifications stand — no overclaiming.

HIPAAActive

Compliant · BAAs available

SOC 2 Type IIIn Progress

Audit in progress

HITRUST CSFOn Roadmap

On roadmap

HL7 · FHIRCore

Native, by design

AWS HIPAA-eligible infrastructure · Business Associate Agreements (BAAs) · Encryption in transit & at rest · See our security details →

Connects with your entire healthcare ecosystem

EHRs, national networks, payers, pharmacies and devices — over HL7 v2, FHIR, C-CDA, X12, NCPDP and DICOM. If it speaks a healthcare standard, Health1st speaks to it.

EHR Systems

Epic
Oracle Health (Cerner)
athenahealth
eClinicalWorks
Veradigm
MEDITECH
NextGen

HIE / QHIN Networks

Carequality
eHealth Exchange
CommonWell
TEFCA
Health Gorilla

CMS & Payers

Medicare
Medicaid
Commercial payers

Pharmacy & Devices

Surescripts
NCPDP networks
DICOM devices

Product names are trademarks of their respective owners. Listing indicates interoperability, not endorsement or partnership.

Get quick answers to common questions

Quick answers about our platform

Ready to turn months of interface work into days?

See a live HL7 v2 ↔ FHIR translation on your own message types. No obligation.

Talk to our team